Proje Geliştirme ve
Koordinasyon Birimi

2016-03-14 United Kingdom:Diagnosis and Treatment for an Auto-Antibody - Induced Inflammation Enhancement in Rheumatoid Diseases


Diagnosis and Treatment for an Auto-Antibody - Induced Inflammation Enhancement in Rheumatoid Diseases

Description of the project offered: 
We have discovered an auto-antibody based new biomarker. Our investigation has shown that it plays a strong pathological role in inflammatory diseases such as sepsis shock, RA and other inflammatory diseases. We found that 90% patients of sepsis shock in ICU will die if the patients are positive for the auto-antibody. Preliminary data from us show that this auto-antibody is strongly related to RA.
The ultimate goal of this project is to develop diagnostic methods to monitor the auto-antibody in RA and other rheumatoid diseases; moreover, we intend to develop therapeutic agents to neutralize the auto-antibody and to induce tolerance of the B cells that produce the auto-antibody. We will performe a corhort study to validate the correlatioship between the auto-antibody and rheumatoid arthritis.
Project proposer:   Shisong Jiang ()
Partner role:  Project coordinator 
Partner organisation:  Research
Call for proposal title:  N/A 

Description of the collaboration sought: 

Expertise sought: Veterinary and animal sciences, Medical biotechnology, Life sciences, Biotechnology, Medicine. Health, 
Roles sought: Project coordinator, 
Organisation types sought: Industry, Research, Technology transfer, Small or medium-sized enterprise (SME), 
Countries sought: Austria, Belgium, Bulgaria, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, United Kingdom, Albania, Bosnia and Herzegovina, Croatia, Iceland, Israel, Liechtenstein, Macedonia, the former Yugoslav Republic of, Montenegro, Norway, Serbia, Switzerland, Turkey