Proje Geliştirme ve
Koordinasyon Birimi

2016-01-28 Egypt: Equine Tendon Enjury

2016-01-28 Egypt: Equine Tendon Enjury

Description of the project offered: 
Tendons are mechanically responsible for transmitting muscle forces to bone, and in doing so, permit locomotion and enhance joint stability. Moreover, tendons are a living tissue and respond to mechanical forces by changing their metabolism as well as their structural and mechanical properties.
Tendon overuse injuries, which are collectively referred to as tendinopathy, affect millions of people in occupational and athletic settings. Despite this, there are few studies on non-traumatic, overuse tendon injuries. The term ‘‘overuse’’ implies a repetitive stretching of a tendon and results in the inability of the tendon to endure further tension. Although tendinopathy is likely caused by intrinsic or extrinsic factors or in combination, excessive mechanical loading is considered a major causation factor. It is believed that small, repetitive strains, which are below the failure threshold of the tendon, cause tendon microinjuries and subsequently tendon inflammation.
Equine tendon: Injury to the forelimb superficial digital flexor tendon (SDFT) is one of the most common causes of lameness in Thoroughbred racehorses. Lesions range in severity from minor partial unilateral to complete bilateral rupture (Goodship, 1993). Lesions occur most frequently in the core of the mid-metacarpal region, but can involve any site from the musculotendinous junction to the branches of insertion. Tendon injuries have been reported to occur in 0.6–9/1000 Thoroughbred racehorse starts, with incidence rates of 11– 30% (over 1–10 year periods), prolonged intervals out of work (up to 18 months), and high rates of retirement from racing.

the aim of the project is:
• Study the pathological and healing finding of experimental induced tendon injury.
• Evaluation of new biological therapies (PRP and stem cells) on clinical signs, ultrasonographic and histopathological finding in experimentally induced tendon injury
Project proposer:   Ahmed Elmesiry (Egypt)
Partner role:  Project coordinator 
Partner organisation:  Research
Call for proposal title:  N/A 

Description of the collaboration sought: 

Expertise sought: Agriculture, Veterinary and animal sciences, Medical biotechnology, Biotechnology, Medicine. Health, 
Roles sought: Project participant, Project coordinator, 
Organisation types sought: Research, Education, Non-governmental organisation (NGO), 
Countries sought: Austria, Belgium, Bulgaria, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, United Kingdom, Albania, Bosnia and Herzegovina, Croatia, Iceland, Israel, Liechtenstein, Macedonia, the former Yugoslav Republic of, Montenegro, Norway, Serbia, Switzerland, Turkey, Australia, Brazil, Canada, China, Japan, Korea, Democratic People's Republic of, Korea, Republic of, Kuwait, Mexico, New Zealand, South Africa, United Arab Emirates, United States, Virgin Islands, British,